Na de publicatie van de Counterpoint Studie (over de omkeerbaarheid van diabetes type 2 met behulp van een zeer laag calorisch dieet), hebben de auteurs op een website informatie over het omkeren van diabetes ter beschikking gesteld. Hierbij werd ook informatie voor de behandelend arts geplaatst. Kort daarna begonnen mensen feedback te geven over hun persoonlijke ervaringen met hun pogingen diabetes te keren. De informatie is samengebracht om de resultaten die gemotiveerde mensen met diabetes type 2 met een laag calorisch dieet kunnen bereiken buiten een onderzoek setting weer te geven.
Population response to information on reversibility of Type 2 diabetes
Authors: Steven S, Lim EL, Taylor R.
Journal: Diabet Med. 2013 Jan 15. doi: 10.1111/dme.12116.
Affiliation: Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon, Tyne, UK.
Abstract: AIMS: Following publication of the Counterpoint Study (on the reversibility of Type 2 diabetes using a very low energy diet), the extent of public interest prompted the authors to make available, on a website, general information about reversing diabetes. Shortly thereafter, individuals began to feed back their personal experiences of attempting to reverse their diabetes. We have collated this information on the effects of energy restriction in motivated individuals with Type 2 diabetes that has been achieved outside a research setting.
METHODS: Emails, letters and telephone communications received between July 2011 and September 2012 were evaluated (n = 77: 66 men, 11 women). Median diabetes duration was 5.5 years (3 months-28 years). Reversal of diabetes was defined as achieving fasting capillary blood glucose < 6.1 mmol/l and/or, if available, HbA(1c) less than 43 mmol/mol (6.1%) off treatment.
RESULTS: Self-reported weight fell from 96.7 ± 17.5 kg at baseline to 81.9 ± 14.8 kg after weight loss (P < 0.001). Self-reported fasting blood glucose levels fell from 8.3 mmol/l (5.9-33.0) to 5.5 mmol/l (4.0-10.0) after the weight loss period (P < 0.001). Diabetes reversal was considered to have occurred in 61% of the population. Reversal of diabetes was observed in 80, 63 and 53% of those with > 20, 10-20 and < 10 kg weight loss, respectively. There was a significant correlation between degree of weight loss and reported fasting glucose levels (Rs -0.38, P = 0.006). Reversal rates according to diabetes duration were: short (< 4 years) = 73%, medium (4-8 years) = 56% and long (> 8 years) = 43%.
CONCLUSION: These data demonstrate that intentional weight loss achieved at home by health-motivated individuals can reverse Type 2 diabetes. Diabetes reversal should be a goal in the management of Type 2 diabetes.
© 2013 The Authors. Diabetic Medicine © 2013 Diabetes UK